BDBM645392 US20240016810, Compound TABLE 16.5::US20240208964, Biochemistry 5

SMILES C1CN(CCO1)c1cc(nc2cc(nn12)-c1ccncc1)-c1cccc(n1)-c1ccccc1

InChI Key InChIKey=LYPMTYMIIFVKSH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 645392   

LigandPNGBDBM645392(US20240016810, Compound TABLE 16.5 | US20240208964...)
Affinity DataIC50: 14nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

LigandPNGBDBM645392(US20240016810, Compound TABLE 16.5 | US20240208964...)
Affinity DataIC50: 14nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Kineta

US Patent
LigandPNGBDBM645392(US20240016810, Compound TABLE 16.5 | US20240208964...)
Affinity DataIC50: 14nMAssay Description:The biochemical PIKfyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo™ Kinase ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Kineta

US Patent
LigandPNGBDBM645392(US20240016810, Compound TABLE 16.5 | US20240208964...)
Affinity DataIC50: 14nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandPNGBDBM645392(US20240016810, Compound TABLE 16.5 | US20240208964...)
Affinity DataIC50: 230nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent