BDBM645402 US20240016810, Compound TABLE 16.15::US20240150358, Example 00181::US20240208964, Biochemistry 15

SMILES C(Oc1nc(cc(n1)-c1nccc(n1)-c1ccccc1)N1CCOCC1)c1ccncc1

InChI Key InChIKey=SFUFKLMANWQRQD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 645402   

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Kineta

US Patent
LigandPNGBDBM645402(US20240016810, Compound TABLE 16.15 | US2024020896...)
Affinity DataIC50: 32nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandPNGBDBM645402(US20240016810, Compound TABLE 16.15 | US2024020896...)
Affinity DataIC50: 32nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Kineta

US Patent
LigandPNGBDBM645402(US20240016810, Compound TABLE 16.15 | US2024020896...)
Affinity DataIC50: 32nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandPNGBDBM645402(US20240016810, Compound TABLE 16.15 | US2024020896...)
Affinity DataIC50: 32nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Kineta

US Patent
LigandPNGBDBM645402(US20240016810, Compound TABLE 16.15 | US2024020896...)
Affinity DataIC50: 32nMAssay Description:The biochemical PIKfyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo™ Kinase ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM645402(US20240016810, Compound TABLE 16.15 | US2024020896...)
Affinity DataIC50: 1.45E+3nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent