BDBM645454 N-(4-{[6-(5-chloro-2- fluorophenyl)-3- methylpyridazin-4- yl]amino}pyridin-2-yl)-3-[4- (2,2,2- trifluoroethyl)piperazin-1- yl]propanamide::US20240018122, Example 124

SMILES Cc1nnc(cc1Nc1ccnc(NC(=O)CCN2CCN(CC(F)(F)F)CC2)c1)-c1cc(Cl)ccc1F

InChI Key InChIKey=IYSZDMHOMJNCLI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645454   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645454(N-(4-{[6-(5-chloro-2- fluorophenyl)-3- methylpyrid...)
Affinity DataIC50: <1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent