BDBM645520 N-{6-[2-fluoro-5-(propan-2- yl)phenyl]pyridazin-4-yl}-7- [2-(4-methylpiperazin-1-yl)- ethoxy]quinolin-4-amine::US20240018122, Example 37

SMILES CC(C)c1ccc(F)c(c1)-c1cc(Nc2ccnc3cc(OCCN4CCN(C)CC4)ccc23)cnn1

InChI Key InChIKey=OEYWMVKCMARLOK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645520   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645520(US20240018122, Example 37 | N-{6-[2-fluoro-5-(prop...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent