BDBM645521 N-[6-(5-chloro-2-fluorophen- yl)pyridazin-4-yl]-7-{2-[4- (2,2,2-trifluoroethyl)piperazin- 1-yl]ethoxy}quinolin-4-amine::US20240018122, Example 41

SMILES Fc1ccc(Cl)cc1-c1cc(Nc2ccnc3cc(OCCN4CCN(CC(F)(F)F)CC4)ccc23)cnn1

InChI Key InChIKey=AUKYSRWKIXPYKF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645521   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645521(US20240018122, Example 41 | N-[6-(5-chloro-2-fluor...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
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Date in BDB:
3/13/2024
Entry Details
US Patent