BDBM645525 N-[6-(5-chloro-2-fluorophen- yl)pyridazin-4-yl]-7-(2-{5- methyl-octahydropyrrolo[3,4- c]pyrrol-2-yl}ethoxy)quinolin- 4-amine::US20240018122, Example 55

SMILES CN1CC2CN(CCOc3ccc4c(Nc5cnnc(c5)-c5cc(Cl)ccc5F)ccnc4c3)CC2C1

InChI Key InChIKey=WHPDAMYOIPSCDL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645525   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645525(US20240018122, Example 55 | N-[6-(5-chloro-2-fluor...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
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Date in BDB:
3/13/2024
Entry Details
US Patent