BDBM645526 1-(3-{2-[(4-{[6-(5-chloro-2- fluorophenyl)pyridazin-4- yl]amino}quinolin-7-yl)- oxy]ethyl}-1,3-diazinan-1- yl)ethan-1-one::US20240018122, Example 56

SMILES CC(=O)N1CCCN(CCOc2ccc3c(Nc4cnnc(c4)-c4cc(Cl)ccc4F)ccnc3c2)C1

InChI Key InChIKey=QDGPZBKPVIPFIV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645526   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645526(US20240018122, Example 56 | 1-(3-{2-[(4-{[6-(5-chl...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
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Date in BDB:
3/13/2024
Entry Details
US Patent