BDBM645538 N-[6-(5-chloro-2-fluorophen- yl)pyridazin-4-yl]-7-[(1-meth- ylpiperidin-4-yl)oxy]quinolin- 4-amine::US20240018122, Example 73

SMILES CN1CCC(CC1)Oc1ccc2c(Nc3cnnc(c3)-c3cc(Cl)ccc3F)ccnc2c1

InChI Key InChIKey=KXOGRJISRANTRG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645538   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645538(US20240018122, Example 73 | N-[6-(5-chloro-2-fluor...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent