BDBM645544 N-[6-(5-chloro-2-fluorophen- yl)pyridazin-4-yl]-7-[(1- methylpiperidin-4-yl)meth- oxy]quinolin-4-amine::US20240018122, Example 89

SMILES CN1CCC(COc2ccc3c(Nc4cnnc(c4)-c4cc(Cl)ccc4F)ccnc3c2)CC1

InChI Key InChIKey=CQXWLPMHDJWTLR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645544   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645544(US20240018122, Example 89 | N-[6-(5-chloro-2-fluor...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent