BDBM645547 4-{[6-(5-chloro-2-fluorophen- yl)pyridazin-4-yl]amino}- quinolin-7-yl 2-methyl-2,7- diazaspiro[3.5]nonane-7- carboxylate::US20240018122, Example 114

SMILES CN1CC2(C1)CCN(CC2)C(=O)Oc1ccc2c(Nc3cnnc(c3)-c3cc(Cl)ccc3F)ccnc2c1

InChI Key InChIKey=MYIPIVJFECKPDC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645547   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645547(US20240018122, Example 114 | 4-{[6-(5-chloro-2-flu...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645547(US20240018122, Example 114 | 4-{[6-(5-chloro-2-flu...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent