BDBM645555 4-{[6-(5-chloro-2-fluorophen- yl)-3-methylpyridazin-4-yl]- amino}quinolin-7-yl 3- (pyrrolidin-1-yl)azetidine-1- carboxylate::US20240018122, Example 152

SMILES Cc1nnc(cc1Nc1ccnc2cc(OC(=O)N3CC(C3)N3CCCC3)ccc12)-c1cc(Cl)ccc1F

InChI Key InChIKey=JBSBKNMDQZONJR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645555   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645555(US20240018122, Example 152 | 4-{[6-(5-chloro-2-flu...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645555(US20240018122, Example 152 | 4-{[6-(5-chloro-2-flu...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent