BDBM645627 US20240018138, Compound 104::US20240018138, Compound 109

SMILES COCC(=O)N1[C@H](C)Cc2[nH]c3c(Cl)c(Cl)ccc3c2[C@@H]1C

InChI Key InChIKey=DSDHEJULZLPMMU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645627   

TargetCyclic GMP-AMP synthase(Human)
Ventus Therapeutics U.S.

US Patent
LigandPNGBDBM645627(US20240018138, Compound 109 | US20240018138, Compo...)
Affinity DataIC50: 15.1nMAssay Description:Certain compounds of the present disclosure were tested for their h-cGAS inhibition activity using the methodology reported in Lama et al., “Dev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Ventus Therapeutics U.S.

US Patent
LigandPNGBDBM645627(US20240018138, Compound 109 | US20240018138, Compo...)
Affinity DataIC50: 51.7nMAssay Description:Certain compounds of the present disclosure were tested for their h-cGAS inhibition activity using the methodology reported in Lama et al., “Dev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent