BDBM645641 US20240018138, Compound 117

SMILES COCC(=O)N1Cc2c(C[C@@H]1C)[nH]c1c(Cl)c(Cl)cc(-c3ccn(C)n3)c21

InChI Key InChIKey=CVCDNMXRHKRQFO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645641   

TargetCyclic GMP-AMP synthase(Human)
Ventus Therapeutics U.S.

US Patent
LigandPNGBDBM645641(US20240018138, Compound 117)
Affinity DataIC50: 221nMAssay Description:Certain compounds of the present disclosure were tested for their h-cGAS inhibition activity using the methodology reported in Lama et al., “Dev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent