BDBM645695 N-(trans-4-hydroxycyclohexyl)-8-(2- (2,2,2-trifluoroethoxy)phenyl)-6- (trifluoromethyl)imidazo[1,2- a]pyridine-2-carboxamide::US20240018140, Compound 36

SMILES O[C@H]1CC[C@@H](CC1)NC(=O)c1cn2cc(cc(-c3ccccc3OCC(F)(F)F)c2n1)C(F)(F)F

InChI Key InChIKey=UISYSJOUHUKGCK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645695   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645695(US20240018140, Compound 36 | N-(trans-4-hydroxycyc...)
Affinity DataEC50:  2.10nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
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