BDBM645782 US20240018153, Compound I-26

SMILES Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@H]1CCN(C1)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1OC(F)F

InChI Key InChIKey=DXCOFPYHHRKXAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645782   

TargetCytoplasmic tyrosine-protein kinase BMX(Human)
2692372 Ontario

US Patent
LigandPNGBDBM645782(US20240018153, Compound I-26)
Affinity DataIC50: 10nMAssay Description:BMX Kinase activity was monitored using a HTRF KinEASE-TK kit from Cisbio (62TK0PEC). The buffer used was 1 kinase buffer supplemented with 2 mM MnCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
2692372 Ontario

US Patent
LigandPNGBDBM645782(US20240018153, Compound I-26)
Affinity DataIC50: 10nMAssay Description:FGFR4 Kinase activity was monitored using a HTRF KinEASE-TK kit from Cisbio (62TK0PEC). The buffer used was 1 kinase buffer supplemented with 2 mM Mn...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent