BDBM645816 (R)-2-chloro-N-(5-chloro-6-methoxypyridin-3-yl)-8-methyl-8-(trifluoromethyl)-7,8-dihydro-6H-pyrazolo[1,5-a]pyrrolo[2,3-e]pyrimidine-6-carboxamide::US20240018157, Example 18

SMILES COc1ncc(NC(=O)N2C[C@](C)(c3c2cnc2cc(Cl)nn32)C(F)(F)F)cc1Cl

InChI Key InChIKey=GMFXWGHPAKILJU-MRXNPFEDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645816   

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
SchröDinger

US Patent
LigandPNGBDBM645816((R)-2-chloro-N-(5-chloro-6-methoxypyridin-3-yl)-8-...)
Affinity DataIC50: <10nMAssay Description:The final assay buffer includes 1 nM of MALT1 full-length protein, 50 μM Ac-LRSR-AMC substrate, 50 mM Tris pH 7.5, 600 mM Sodium Citrate, 1 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
SchröDinger

US Patent
LigandPNGBDBM645816((R)-2-chloro-N-(5-chloro-6-methoxypyridin-3-yl)-8-...)
Affinity DataIC50: <10nMAssay Description:The final assay buffer includes 2 nM of MALT1 full-length protein, 50 μM Ac-LRSR-AMC substrate, 50 mM Tris pH 7.5, 600 mM Sodium Citrate, 1 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent