BDBM646129 US11878965, Example 114::methyl (2-(5-((1R,2R,4S)-2- amino-7-azabicyclo[2.2.1] heptane-7- carbonyl)-7-methoxy-1-methyl- 1H-benzo[d]imidazol-2-yl)-1- (cyclopropylmethyl)-1H-indol-6- yl)(methyl)carbamate

SMILES COC(=O)N(C)c1ccc2cc(-c3nc4cc(cc(OC)c4n3C)C(=O)N3[C@H]4CC[C@@H]3[C@H](N)C4)n(CC3CC3)c2c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646129   

TargetProtein-arginine deiminase type-4(Human)
Gilead Sciences

US Patent
LigandPNGBDBM646129(US11878965, Example 114 | methyl (2-(5-((1R,2R,4S)...)
Affinity DataIC50: 34.5nMAssay Description:One hundred nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well black OptiPlate using a Labcyte E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2024
Entry Details
US Patent