BDBM646195 N-((R)-1-(2-(5-((R)-5-amino-2- methylhexahydropyridazine-1- carbonyl)-7-methoxy-1-methyl-1H- benzo[d]imidazol-2-yl)-1- (cyclopropylmethyl)-1H-pyrrolo[2,3- b]pyridin-6-yl)ethyl)pyrimidine-2- carboxamide::US11878965, Example 180

SMILES COc1cc(cc2nc(-c3cc4ccc(nc4n3CC3CC3)[C@@H](C)NC(=O)c3ncccn3)n(C)c12)C(=O)N1C[C@H](N)CCN1C

InChI Key InChIKey=ZEWXIOPXHDYVHT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646195   

TargetProtein-arginine deiminase type-4(Human)
Gilead Sciences

US Patent
LigandPNGBDBM646195(US11878965, Example 180 | N-((R)-1-(2-(5-((R)-5-am...)
Affinity DataIC50: 28.8nMAssay Description:One hundred nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well black OptiPlate using a Labcyte E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2024
Entry Details
US Patent