BDBM646664 N-[5-(2,2-difluoroethyl)-4,6- dimethoxy-pyrimidin-2-yl]-1H- pyrrolo[3,2-h]quinoline-3- sulfonamide::US20240025883, Example 169

SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c2ccc2cccnc32)nc(OC)c1CC(F)F

InChI Key InChIKey=PDDNXZZNJOWQEH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646664   

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646664(N-[5-(2,2-difluoroethyl)-4,6- dimethoxy-pyrimidin-...)
Affinity DataIC50: 20nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent