BDBM646726 6-bromo-N-[4-methoxy-5- (1,1,2- trifluoroethoxy)pyrimidin-2- yl]-1H-pyrrolo[2,3-b]pyridine- 3-sulfonamide::US20240025883, Example 231

SMILES COc1nc(NS(=O)(=O)c2c[nH]c3nc(Br)ccc23)ncc1OC(F)(F)CF

InChI Key InChIKey=SCSFAIDEHOBMIQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646726   

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646726(6-bromo-N-[4-methoxy-5- (1,1,2- trifluoroethoxy)py...)
Affinity DataIC50: 21nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent