BDBM647494 US20240025893, Example b-04-20

SMILES COc1cccc(n1)C(=O)N1CCN([C@H]2C[C@H](C2)C(=O)Nc2nc3ccc(cc3s2)-c2cnc(CO[C@H]3CCC[C@@H]3O)nc2)[C@@H](C)C1

InChI Key InChIKey=CJILJNONYSEXHA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647494   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Asahi Kasei Pharma

US Patent
LigandPNGBDBM647494(US20240025893, Example b-04-20)
Affinity DataIC50: 1.12nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent