BDBM647510 US20240025893, Example b-04-36

SMILES C[C@H]1CN(CCN1[C@H]1C[C@H](C1)C(=O)Nc1nc2ccc(cc2s1)-c1cnc(CO[C@H]2CCC[C@@H]2O)nc1)C(=O)c1coc(C)n1

InChI Key InChIKey=QKOYDUIRGONJFL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647510   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Asahi Kasei Pharma

US Patent
LigandPNGBDBM647510(US20240025893, Example b-04-36)
Affinity DataIC50: 0.900nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent