BDBM647619 (R)-3-methyl-4-(1-(methylsulfonyl)-6-(1H-pyrazol-3-yl)-1H-pyrrolo[3,2-c][1,7]naphthyridin-4-yl)morpholine ::US20240025899, Compound 8

SMILES C[C@@H]1COCCN1c1nc2c(nccc2c2n(ccc12)S(C)(=O)=O)-c1cc[nH]n1

InChI Key InChIKey=OXWFVOLJDCSTJS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647619   

TargetSerine/threonine-protein kinase ATR [14-953](Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM647619(US20240025899, Compound 8 | (R)-3-methyl-4-(1-(met...)
Affinity DataIC50: 40nMAssay Description:In this experiment, the phosphorylation level of substrate protein P53 (Eurofins, 14-952) was detected by HTRF technology to measure the activity of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent