BDBM647621 Synthesis of (R)-3-methyl-4-(1-methyl-6-(1H-pyrazol-3-yl)-tetrahydropyrazolo[3,4-b]pyrrolo[2,3-d]pyridin-4-yl)morpholine ::US20240025899, Compound 12

SMILES C[C@@H]1COCCN1c1nc2n(ncc2c2N(C)CCc12)-c1cc[nH]n1

InChI Key InChIKey=KPJOUXQOLXEBIF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647621   

TargetSerine/threonine-protein kinase ATR [14-953](Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM647621(US20240025899, Compound 12 | Synthesis of (R)-3-me...)
Affinity DataIC50: 14nMAssay Description:In this experiment, the phosphorylation level of substrate protein P53 (Eurofins, 14-952) was detected by HTRF technology to measure the activity of ...More data for this Ligand-Target Pair
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Date in BDB:
3/19/2024
Entry Details
US Patent