BDBM647662 (S)-2-(bicyclo[2.1.1]hexan-1-yl)-5- (pyrazin-2-yl)-2,5,6,7-tetrahydro-3H- pyrrolo[2,1-c][1,2,4]triazol-3-one::US20240025912, Compound 1-61

SMILES O=c1n2[C@@H](CCc2nn1C12CC(C1)CC2)c1cnccn1

InChI Key InChIKey=PNGYIMFRZFRDOR-JYHUIVOISA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647662   

TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM647662((S)-2-(bicyclo[2.1.1]hexan-1-yl)-5- (pyrazin-2-yl)...)
Affinity DataEC50:  696nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent