BDBM647666 (S)-5-(3-chlorophenyl)-2-(3- fluorobicyclo[1.1.1]pentan-1-yl)- 2,5,6,7-tetrahydro-3H-pyrrolo[2,1- c][1,2,4]triazol-3-one::US20240025912, Compound 1-63

SMILES FC12CC(C1)(C2)n1nc2CC[C@@H](c3cccc(Cl)c3)n2c1=O

InChI Key InChIKey=WMSMYBYPXAUROK-JQRITLKVSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647666   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM647666((S)-5-(3-chlorophenyl)-2-(3- fluorobicyclo[1.1.1]p...)
Affinity DataEC50:  68.1nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent