BDBM647670 (R)-3-(5-(3,5-difluorophenyl)-3-oxo- 5,6-dihydrothiazolo[2,3- c][1,2,4]triazol-2(3H)- yl)bicyclo[1.1.1]pentane-1-carbonitrile::US20240025912, Compound 1-65

SMILES Fc1cc(F)cc(c1)[C@@H]1CSc2nn(c(=O)n12)C12CC(C1)(C2)C#N

InChI Key InChIKey=GPJIHLGKGYKTRD-JQRITLKVSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647670   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM647670((R)-3-(5-(3,5-difluorophenyl)-3-oxo- 5,6-dihydroth...)
Affinity DataEC50:  21.1nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent