BDBM647693 3-[(5S)-3-oxo-5-phenyl-6,7-dihydro- 3H-pyrrolo[2,1-c][1,2,4]triazol-2(5H)- yl]bicyclo[1.1.1]pentane-1-carbonitrile::US20240025912, Compound 1-17

SMILES O=c1n2[C@@H](CCc2nn1C12CC(C1)(C2)C#N)c1ccccc1

InChI Key InChIKey=GKWNDCBDJXJQCP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647693   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM647693(US20240025912, Compound 1-17 | 3-[(5S)-3-oxo-5-phe...)
Affinity DataEC50:  36.9nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
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Date in BDB:
3/19/2024
Entry Details
US Patent