BDBM647702 3-[(5S)-5-(3,5-difluorophenyl)-3-oxo- 6,7-dihydro-3H-pyrrolo[2,1- c][1,2,4]triazol-2(5H)-yl]-2,2- difluorobicyclo[1.1.1]pentane-1- carbonitrile::US20240025912, Compound 3-1

SMILES Fc1cc(F)cc(c1)[C@@H]1CCc2nn(c(=O)n12)C12CC(C1)(C#N)C2(F)F

InChI Key InChIKey=YAVWVKWZWRIROL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647702   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM647702(US20240025912, Compound 3-1 | 3-[(5S)-5-(3,5-diflu...)
Affinity DataEC50:  20nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent