BDBM647707 (S)-3-(5-(3-fluorophenyl)-3-oxo-6,7- dihydro-3H-pyrrolo[2,1- c][1,2,4]triazol-2(5H)- yl)bicyclo[1.1.1]pentane-1-caronitrile::US20240025912, Compound 1-24

SMILES Fc1cccc(c1)[C@@H]1CCc2nn(c(=O)n12)C12CC(C1)(C2)C#N

InChI Key InChIKey=CBWFTAYNRRBWSE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647707   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM647707(US20240025912, Compound 1-24 | (S)-3-(5-(3-fluorop...)
Affinity DataEC50:  29.7nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent