BDBM647743 (S)-2-(3-chlorobicyclo[1.1.1]pentan-1- yl)-5-(3-fluorophenyl)-2,5,6,7- tetrahydro-3H-pyrrolo[2,1- c][1,2,4]triazol-3-one::US20240025912, Compound 1-42

SMILES Fc1cccc(c1)[C@@H]1CCc2nn(c(=O)n12)C12CC(Cl)(C1)C2

InChI Key InChIKey=SSVISRLKBJSUPR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647743   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM647743(US20240025912, Compound 1-42 | (S)-2-(3-chlorobicy...)
Affinity DataEC50:  18.5nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent