BDBM647772 (S)-2-(3-chlorobicyclo[1.1.1]pentan-1- yl)-5-(pyrazin-2-yl)-2,5,6,7-tetrahydro- 3H-pyrrolo[2,1-c][1,2,4]triazol-3-one::US20240025912, Compound 1-59

SMILES ClC12CC(C1)(C2)n1nc2CC[C@@H](c3cnccn3)n2c1=O

InChI Key InChIKey=ZGOYJGVSZYRKIV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647772   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM647772(US20240025912, Compound 1-59 | (S)-2-(3-chlorobicy...)
Affinity DataEC50:  53.9nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent