BDBM649003 5-(6-Chloro-5-(4-(methylsulfonyl)piperazin-1-yl)-1H-indazol-1-yl)-2-fluoro-3-(trifluoromethyl)phenol::US20240034736, Compound 19

SMILES CS(=O)(=O)N1CCN(CC1)c1cc2cnn(-c3cc(O)c(F)c(c3)C(F)(F)F)c2cc1Cl

InChI Key InChIKey=XOIXHHOENVLUCA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 649003   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Fl2022-001

US Patent
LigandPNGBDBM649003(5-(6-Chloro-5-(4-(methylsulfonyl)piperazin-1-yl)-1...)
Affinity DataIC50: 100nMAssay Description:HSD17b13 enzyme was diluted in 1× assay buffer to the desired enzyme concentration based on the specific activity of the enzyme lot. 20 uL of diluted...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent