BDBM649050 2,6-Difluoro-3-(5-(7-methoxy-4- azaspiro[2.5]octan-4-yl)-3-methyl-1H- pyrazolo[3,4-c]pyridin-1-yl)-5- (trifluoromethyl)phenol::US20240034736, Compound 19.52

SMILES COC1CCN(c2cc3c(C)nn(-c4cc(c(F)c(O)c4F)C(F)(F)F)c3cn2)C2(CC2)C1

InChI Key InChIKey=IFDHEALJLLDEBH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 649050   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Fl2022-001

US Patent
LigandPNGBDBM649050(2,6-Difluoro-3-(5-(7-methoxy-4- azaspiro[2.5]octan...)
Affinity DataIC50: 100nMAssay Description:HSD17b13 enzyme was diluted in 1× assay buffer to the desired enzyme concentration based on the specific activity of the enzyme lot. 20 uL of diluted...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent