BDBM649058 3-(5-(4-(2-(Dimethylamino)ethoxy)piperidin-1- yl)-3-methyl-1H-pyrazolo[3,4-c]65yridine-1- yl)-2,6-difluoro-5-(trifluoromethyl)phenol::US20240034736, Compound 19.60

SMILES CN(C)CCOC1CCN(CC1)c1cc2c(C)nn(-c3cc(c(F)c(O)c3F)C(F)(F)F)c2cn1

InChI Key InChIKey=CDMOVYUMWBJDSC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 649058   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Fl2022-001

US Patent
LigandPNGBDBM649058(3-(5-(4-(2-(Dimethylamino)ethoxy)piperidin-1- yl)-...)
Affinity DataIC50: 550nMAssay Description:HSD17b13 enzyme was diluted in 1× assay buffer to the desired enzyme concentration based on the specific activity of the enzyme lot. 20 uL of diluted...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent