BDBM649069 2,6-Difluoro-3-(3-methoxy-5- (methyl(tetrahydro-2H-pyran-4-yl)amino)-1H- indazol-1-yl)-5-(trifluoromethyl)phenol::US20240034736, Compound 19.72

SMILES COc1nn(-c2cc(c(F)c(O)c2F)C(F)(F)F)c2ccc(cc12)N(C)C1CCOCC1

InChI Key InChIKey=RAIRREVACKHDDT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 649069   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Fl2022-001

US Patent
LigandPNGBDBM649069(2,6-Difluoro-3-(3-methoxy-5- (methyl(tetrahydro-2H...)
Affinity DataIC50: 550nMAssay Description:HSD17b13 enzyme was diluted in 1× assay buffer to the desired enzyme concentration based on the specific activity of the enzyme lot. 20 uL of diluted...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent