BDBM649082 2-Fluoro-5-(3-methyl-5-(7-oxa-4- azaspiro[2.5]octan-4-yl)-1H-pyrazolo[3,4- c]pyridin-1-yl)-3-(trifluoromethyl)phenol::US20240034736, Compound 19.85

SMILES Cc1nn(-c2cc(O)c(F)c(c2)C(F)(F)F)c2cnc(cc12)N1CCOCC11CC1

InChI Key InChIKey=PWGIALXANXJTCM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 649082   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Fl2022-001

US Patent
LigandPNGBDBM649082(2-Fluoro-5-(3-methyl-5-(7-oxa-4- azaspiro[2.5]octa...)
Affinity DataIC50: 100nMAssay Description:HSD17b13 enzyme was diluted in 1× assay buffer to the desired enzyme concentration based on the specific activity of the enzyme lot. 20 uL of diluted...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent