BDBM649163 5-(5-(6-Azaspiro[2.5]octan-6-yl)-1H- pyrazolo[3,4-c]pyridine-1-yl)-2-fluoro-3- (trifluoromethyl)phenol::US20240034736, Compound 21.44

SMILES Oc1cc(cc(c1F)C(F)(F)F)-n1ncc2cc(ncc12)N1CCC2(CC2)CC1

InChI Key InChIKey=VHLXDOLDSIZEAQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 649163   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Fl2022-001

US Patent
LigandPNGBDBM649163(5-(5-(6-Azaspiro[2.5]octan-6-yl)-1H- pyrazolo[3,4-...)
Affinity DataIC50: 100nMAssay Description:HSD17b13 enzyme was diluted in 1× assay buffer to the desired enzyme concentration based on the specific activity of the enzyme lot. 20 uL of diluted...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent