BDBM649672 5-((4-chloro-2-(((2-hydroxyethyl)amino)methyl)-5-((3′-(3-(4-(((2-hydroxyethyl)amino)methyl)-1H-1,2,3-triazol-1-yl)propoxy)-2,2′-dimethyl-[1,1′-biphenyl]-3-yl)methoxy) phenoxy) methyl)nicotinonitrile::US20240043392, Compound II-2

SMILES Cc1c(COc2cc(OCc3cncc(c3)C#N)c(CNCCO)cc2Cl)cccc1-c1cccc(OCCCn2cc(CNCCO)nn2)c1C

InChI Key InChIKey=RFGPFARMWDVXRV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 649672   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Xi'An Xinton Pharmaceutcal Research

US Patent
LigandPNGBDBM649672(5-((4-chloro-2-(((2-hydroxyethyl)amino)methyl)-5-(...)
Affinity DataIC50: 55nMAssay Description:A negative control, a positive control and drug administration groups were set up, with two duplicate wells in each group. For the positive control g...More data for this Ligand-Target Pair
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Date in BDB:
4/12/2024
Entry Details
US Patent