BDBM649676 1-(4-((3′-(3-(4-((2-carbamoylpyrrolidin-1-yl)methyl)-1H-1,2,3-triazol-1-yl) Propoxy)-2,2′-dimethyl-[1,1′-biphenyl]-3-methoxy)-5-chloro-2-((5-cyanopyridin-3-yl)methoxy))benzyl)) pyrrolidine-2-carboxamide::US20240043392, Compound II-4

SMILES Cc1c(COc2cc(OCc3cncc(c3)C#N)c(CN3CCCC3C(N)=O)cc2Cl)cccc1-c1cccc(OCCCn2cc(CN3CCCC3C(N)=O)nn2)c1C

InChI Key InChIKey=DFBHSFAAVICURP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 649676   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Xi'An Xinton Pharmaceutcal Research

US Patent
LigandPNGBDBM649676(1-(4-((3′-(3-(4-((2-carbamoylpyrrolidin-1-yl...)
Affinity DataIC50: 55nMAssay Description:A negative control, a positive control and drug administration groups were set up, with two duplicate wells in each group. For the positive control g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent