BDBM649686 (R)-1-((1-(3-((3′-((2-chloro-4-(((R)-3-hydroxypiperidin-1-yl)methyl)-5-methoxyl phenoxy)methyl)-2,2′-dimethyl-[1,1′-biphenyl]-3-yl)oxy)propyl)-1H-1,2,3-triazol-4-yl)methyl)piperidin-3-ol::US20240043392, Compound II-14

SMILES COc1cc(OCc2cccc(c2C)-c2cccc(OCCCn3cc(CN4CCC[C@@H](O)C4)nn3)c2C)c(Cl)cc1CN1CCC[C@@H](O)C1

InChI Key InChIKey=GTVKWTVYHLVXNS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 649686   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Xi'An Xinton Pharmaceutcal Research

US Patent
LigandPNGBDBM649686((R)-1-((1-(3-((3′-((2-chloro-4-(((R)-3-hydro...)
Affinity DataIC50: 55nMAssay Description:A negative control, a positive control and drug administration groups were set up, with two duplicate wells in each group. For the positive control g...More data for this Ligand-Target Pair
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Date in BDB:
4/12/2024
Entry Details
US Patent