BDBM649687 (4-((3′-(3-(4-(((1-carboxyethyl)amino)methyl)-1H-1,2,3-triazol-1-yl)propoxy)-2 ,2′-dimethyl-[1,1′-biphenyl]-3-yl)methoxy)-5-chloro-2-methoxybenzyl)alanine::US20240043392, Compound II-15

SMILES COc1cc(OCc2cccc(c2C)-c2cccc(OCCCn3cc(CNC(C)C(O)=O)nn3)c2C)c(Cl)cc1CN[C@@H](C)C(O)=O

InChI Key InChIKey=AGOIUPCCIJJUJA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 649687   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Xi'An Xinton Pharmaceutcal Research

US Patent
LigandPNGBDBM649687((4-((3′-(3-(4-(((1-carboxyethyl)amino)methyl...)
Affinity DataIC50: 5nMAssay Description:A negative control, a positive control and drug administration groups were set up, with two duplicate wells in each group. For the positive control g...More data for this Ligand-Target Pair
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Date in BDB:
4/12/2024
Entry Details
US Patent