BDBM649688 (4-((3′-(3-(4-(((1-carboxy-2-hydroxyethyl)amino)methyl)-1H-1,2,3-triazol-1-yl)propoxyl)-2,2′-dichloro-[1,1′-biphenyl]-3-yl)methoxy)-5-chloro-2-((5-cyanopyridin-3-yl)methoxy)benzyl)serine::US20240043392, Compound II-16

SMILES OCC(NCc1cn(CCCOc2cccc(c2Cl)-c2cccc(COc3cc(OCc4cncc(c4)C#N)c(CN[C@@H](CO)C(O)=O)cc3Cl)c2Cl)nn1)C(O)=O

InChI Key InChIKey=UCAOFEMFDODGLV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 649688   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Xi'An Xinton Pharmaceutcal Research

US Patent
LigandPNGBDBM649688((4-((3′-(3-(4-(((1-carboxy-2-hydroxyethyl)am...)
Affinity DataIC50: 55nMAssay Description:A negative control, a positive control and drug administration groups were set up, with two duplicate wells in each group. For the positive control g...More data for this Ligand-Target Pair
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Date in BDB:
4/12/2024
Entry Details
US Patent