BDBM649689 (4-((3′-(3-(4-(((carboxymethyl)amino)methyl)-1H-1,2,3-triazol-1-yl)propoxy)-2, 2′-dichloro-[1,1′-biphenyl]-3-yl)methoxy)-5-chloro-2-((5-cyanopyridin-3-yl)methoxy)benzyl) glycine::US20240043392, Compound II-17

SMILES NCC(=O)OCc1cc(Cl)c(OCc2cccc(c2Cl)-c2cccc(OCCCn3cc(CNCC(O)=O)nn3)c2Cl)cc1OCc1cncc(c1)C#N

InChI Key InChIKey=ZMOKQFQUGMRSCY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 649689   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Xi'An Xinton Pharmaceutcal Research

US Patent
LigandPNGBDBM649689((4-((3′-(3-(4-(((carboxymethyl)amino)methyl)...)
Affinity DataIC50: 550nMAssay Description:A negative control, a positive control and drug administration groups were set up, with two duplicate wells in each group. For the positive control g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent