BDBM649705 3-fluoro-5-formyl-4-hydroxy- N-(5-(3-(pyrrolidin-1- yl)phenyl)thiazol-2- yl)benzamide::US20240043395, Compound 12

SMILES Oc1c(F)cc(cc1C=O)C(=O)Nc1ncc(s1)-c1cccc(c1)N1CCCC1

InChI Key InChIKey=WRBCJFIKTXONAZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 649705   

TargetToll-like receptor 9(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649705(3-fluoro-5-formyl-4-hydroxy- N-(5-(3-(pyrrolidin-1...)
Affinity DataIC50: 200nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

TargetToll-like receptor 2(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649705(3-fluoro-5-formyl-4-hydroxy- N-(5-(3-(pyrrolidin-1...)
Affinity DataIC50: 600nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

TargetToll-like receptor 6(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649705(3-fluoro-5-formyl-4-hydroxy- N-(5-(3-(pyrrolidin-1...)
Affinity DataIC50: 600nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent