BDBM649751 3-fluoro-5-formyl-4-hydroxy- N-(3-(4-(pyrrolidin-1- yl)phenyl)-1,2,4-thiadiazol-5- yl)benzamide::US20240043395, Compound 167

SMILES Oc1c(F)cc(cc1C=O)C(=O)Nc1nc(ns1)-c1ccc(cc1)N1CCCC1

InChI Key InChIKey=RTOSOVQNEONXAC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 649751   

TargetToll-like receptor 2(Homo sapiens (Human))
Neuropore Therapies

US Patent
LigandPNGBDBM649751(3-fluoro-5-formyl-4-hydroxy- N-(3-(4-(pyrrolidin-1...)
Affinity DataIC50:  1.50E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 9(Homo sapiens (Human))
Neuropore Therapies

US Patent
LigandPNGBDBM649751(3-fluoro-5-formyl-4-hydroxy- N-(3-(4-(pyrrolidin-1...)
Affinity DataIC50:  500nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 6(Homo sapiens)
Neuropore Therapies

US Patent
LigandPNGBDBM649751(3-fluoro-5-formyl-4-hydroxy- N-(3-(4-(pyrrolidin-1...)
Affinity DataIC50:  600nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent