BDBM649818 US20240043403, Example 55

SMILES CN1CCN(C[C@H]1CN)c1c(NC(=O)c2coc(n2)-c2ccnnc2)ccc(Oc2ccccc2F)c1C(F)(F)F

InChI Key InChIKey=RFDXASRMRUIQLM-QGZVFWFLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 649818   

TargetDiacylglycerol kinase delta(Human)
Astellas Pharma

US Patent
LigandPNGBDBM649818(US20240043403, Example 55)
Affinity DataIC50:  12nMAssay Description:To a 384-well plate (Greiner Bio-One Co., Ltd.), 3 μL of a DGK ξ enzyme dissolved in an assay buffer (40 mM Tris-HCl pH 7.5, 10 mM MgCl2, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent