BDBM650150 US20240043427, Example 238

SMILES Fc1ccc(NC(=O)OCC(F)(F)COc2cc(nn3ccnc23)-c2c[nH]c(=O)[nH]c2=O)c(F)c1

InChI Key InChIKey=YGBXXEYDRZRNFR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 650150   

Target5'-nucleotidase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM650150(US20240043427, Example 238)
Affinity DataIC50: 0.360nMAssay Description:Compound serial dilutions were pre-spotted into Thermo Nunc assay plate. 50 uL CD73 enzyme buffer (CD73 purchased from R&D system=0.6 nM, 25 mM Tris,...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent