BDBM650154 US20240043427, Example 242

SMILES O=c1[nH]cc(-c2cc(N3CCC(C3)Oc3ccccc3)c3nccn3n2)c(=O)[nH]1

InChI Key InChIKey=RSPWSQXIWWAACU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 650154   

Target5'-nucleotidase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM650154(US20240043427, Example 242)
Affinity DataIC50: 0.220nMAssay Description:Compound serial dilutions were pre-spotted into Thermo Nunc assay plate. 50 uL CD73 enzyme buffer (CD73 purchased from R&D system=0.6 nM, 25 mM Tris,...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent