BDBM650365 US20240043427, Example 460

SMILES FC(F)(F)Cn1ncc2c(Cl)cc(cc12)[C@H]1C[C@@H]1c1cc(nn2ccnc12)-c1c[nH]c(=O)[nH]c1=O

InChI Key InChIKey=UQOUSZYFZVDDAF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 650365   

Target5'-nucleotidase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM650365(US20240043427, Example 460)
Affinity DataIC50: 0.460nMAssay Description:Compound serial dilutions were pre-spotted into Thermo Nunc assay plate. 50 uL CD73 enzyme buffer (CD73 purchased from R&D system=0.6 nM, 25 mM Tris,...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent